Action anticandidosique des huiles essentielles : Leur utilisation concomitante avec des médicaments antifongiques
The anticandida effect of essential oils used with antifungal drugs
Essential oils have been used for many years in alternative medicine for their antimicrobial properties, and especially for their antifungal activity. The antifungal action of these vegetable secretions has been observed through many in vitro studies. However, the various methods used do not allow a comparison between the essential oils tested. With a statistical method, it is possible to determine very precisely the Minimal Inhibitory Concentration (MIC 80%) of the oils which were tested. A comparative study of the antifungal properties of various essential oils has been carried out. Moreover, the use of an essential oil with amphotericin B (AmB) provoked a strong drop in the MIC 80% of AmB. These results may mean that giving a smaller dose of AmB in the treatment of mycosis is possible, which reduces its side effects.
R. GIORDANI, J. KALOUSTIAN
Antifungal activity, Essential oils, Candidaalbicans , Amphotericin B